منابع مشابه
An unusual case of cardiac glycoside toxicity.
a Cardiovascular Disease Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD, United States b Pulmonary Disease and Critical Care Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD, United States c Internal Medicine Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD, United ...
متن کاملINOTROPY AND TOXICITY OF A POLAR CARDIAC GLYCOSIDE/Mudge
17. Ito CS, Scher AM: Reflexes from the aortic baroreceptor fibers in the cervical vagus of the cat and dog. Circ Res 34: 51-60, 1974 18. Thoren PN, Mancia G, Shepherd JT: Vasomotor inhibition in rabbits by vagal nonmedullated fibers from cardiopulmonary area. Am J Physiol 229: 1410-1413, 1975 19. Paintal AS: Vagal sensory receptors and their reflex effects. Physiol Rev 53: 159-227, 1973 20. Ob...
متن کاملCaMKII Mediates Digitalis - Induced Arrhythmias
Background Digitalis-induced Na accumulation results in an increase in Cai via the Na/Ca exchanger leading to enhanced SR Ca load, responsible for the positive inotropic and toxic arrhythmogenic effects of glycosides. Digitalis-induced increase in Cai could also activate CaMKII which has been shown to have proarrhythmic effects. Here we investigate whether CaMKII underlies digitalis-induced arr...
متن کاملCaMKII Mediates Digitalis - Induced Arrhythmias Running title :
Background Digitalis-induced Na accumulation results in an increase in Cai via the Na/Ca exchanger leading to enhanced SR Ca load, responsible for the positive inotropic and toxic arrhythmogenic effects of glycosides. Digitalis-induced increase in Cai could also activate CaMKII which has been shown to have proarrhythmic effects. Here we investigate whether CaMKII underlies digitalis-induced arr...
متن کاملSerum Cardiac Glycoside Assay Based
An assay of serum digoxin and other cardiac glycosides by displacement of 3Houabain from Na-K ATPase is described. It is rapidly set up by any laboratory with a liquid scintillation counter. It can also assay digitalis leaf, digitoxin, and gitalin (Gitaligin), and has uncovered unsuspected administration of them. The assay takes less than 1 hour. No quench correction of counts is required. One ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2011
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.12.1782